PP1 beta Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4364-20, A4364-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
Synonyms: MP; PP1B; PP1c; NSLH2; PP-1B; PPP1CD; PP1beta; PPP1beta; HEL-S-80p; PP1 beta
GeneID: 5500
Swiss-Prot: P62140
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 37kDa
Observed Molecular Weight: 37kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 228-327 of human PP1 beta (P62140).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:500 - 1:1000 | IF/ICC: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Translation Control, Cancer, Signal Transduction, MAPK-Erk Signaling Pathway, Endocrine Metabolism, Lipid Metabolism, Insulin Receptor Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Dopamine Signaling in Parkinson's Disease
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: PC-3, U-251MG, Mouse brain, Rat testis, Rat brain, Rat heart
Cellular Location: Cytoplasm, Nucleus, Nucleolus, Nucleoplasm
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.