Progesterone Receptor Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A19697-20, A19697-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Synonyms: PR; NR3C3; Progesterone Receptor
GeneID: 5241
Swiss-Prot: P06401
Reactivity: Human
Tested Applications: ELISA, WB, IHC-P
Calculated Molecular Weight: 99kd(CST:90,118KD)
Observed Molecular Weight: 90kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-330 of human Progesterone Receptor (NP_000917.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Nuclear Receptor Signaling, Nuclear hormone receptors, Protein phosphorylation, Cancer, Tumor biomarkers, Signal Transduction, Endocrine Metabolism, Neuroscience
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Cytoplasm, Mitochondrion Outer Membrane, Nucleus
Positive Samples: T-47D
Keywords: 5241, sc-539, sc-7208, sc-538, NR3C3, PGR, PR, progesterone receptor, nuclear receptor subfamily 3 group C member 3, P06401, Progesterone Receptor, Nuclear Receptor Subfamily 3 Group C Member 3, Progesterone Receptor A/B, 病理诊断抗体, IHC pathology, 病理诊断, 病理診斷抗體, 病理診斷
Symbol: PGR
Category: Monoclonal Antibodies
Research Use Only