RNF40 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9598-20, A9598-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: BRE1B; RBP95; STARING; RNF40
GeneID: 9810
Swiss-Prot: O75150
Reactivity: Human, Mouse
Calculated Molecular Weight: 114kDa
Observed Molecular Weight: 130kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 231-431 of human RNF40 (O75150).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones, Cell Biology Developmental Biology, Ubiquitin
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: MCF7, BxPC-3, A375, Mouse brain
Cellular Location: Nucleus
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.