Cadherin-7 (R678) Polyclonal Antibody
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Catalogue Numbers: BS2225-50, BS2225-100
Sizes: 50µl, 100µl
Swiss-Prot: Q9ULB5
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC
Background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-7 is a member of the atypical type II cadherin family that lacks the HAV cell recognition sequence found in type I cadherins. Although the absence of an HAV sequence decreases cell adhesion specificity, cadherin-7 contributes to cell organization by mediating homophilic cell adhesion in the brain, testis and prostate.
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Specificity: Cadherin-7 (R678) polyclonal antibody detects endogenous levels of Cadherin-7 protein.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of Cadherin-7 (R678) pAb at 1:500 dilution
Lane 1: The Brain tissue lysate of Mouse (40ug)
Lane 2: The Brain tissue lysate of Rat (40ug), Immunohistochemistry (IHC) analyzes of Cadherin-7 (R678) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.
Bioworld Molecular Weight: ~ 87 kDa
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Alternative Name: Cadherin-7; CDH7; CDH7L1
Immunogen: Synthetic peptide, corresponding to amino acids 645-693 of Human Cadherin-7.
Conjugate: Unconjugated
Modification: Unmodified