14-3-3 alpha/beta Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9151-20, A9151-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
Synonyms: HS1; GW128; YWHAA; KCIP-1; HEL-S-1; 14-3-3 alpha/beta
GeneID: 7529
Swiss-Prot: P31946
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 28kDa
Observed Molecular Weight: 28kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 147-246 of human 14-3-3 alpha/beta (P31946).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, G protein signaling, Kinase, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, MAPK-JNK Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint, Immunology Inflammation, Neuroscience, Cell Type Marker, Stem Cells, Neuron marker, Synapse marker
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HT-29, A549, NIH/3T3, Jurkat, Mouse brain, Mouse kidney, Rat lung, Rat brain
Cellular Location: Cytoplasm, Membrane, Vacuole
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.