14-3-3 Theta Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A8936-20, A8936-100
Citations, Manuals and SDS Available upon request.
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Synonyms: 1C5; HS1; 14-3-3; 14-3-3 Theta
GeneID: 10971
Swiss-Prot: P27348
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 28kDa
Observed Molecular Weight: 28kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 Theta (P27348).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, MAPK-JNK Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint, Neuroscience, Cell Type Marker, Stem Cells, Neuron marker, Synapse marker
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: C6, U-251MG, Mouse testis, Mouse brain, Rat testis
Cellular Location: Cytoplasm
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.