14-3-3 zeta/YWHAZ Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A24006-20, A24006-100
Citations, Manuals and SDS Available upon request.
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
Synonyms: HEL4; YWHAD; KCIP-1; HEL-S-3; POPCHAS; HEL-S-93; 14-3-3-zeta; 14-3-3 zeta/YWHAZ
GeneID: 7534
Swiss-Prot: P63104
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 19kDa/28kDa
Observed Molecular Weight: 30kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 145-245of human YWHAZ (NP_002267.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Signal Transduction, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, MAPK-JNK Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint, Cytoskeleton, Actins, Immunology Inflammation, Neuroscience, Cell Type Marker, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Neurodegenerative Diseases Markers
Recommended Dilutions: WB: 1:2000 - 1:10000 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Melanosome
Positive Samples: 293T, HeLa, NIH/3T3, Mouse brain, PC-12, Rat brain
Keywords: 7534, sc-31964, sc-1019, 14 3 3 protein zeta/delta, 14-3-3, KCIP 1, YWHAZ, 14-3-3-zeta, HEL-S-3, HEL-S-93, HEL4, KCIP-1, YWHAD, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, 14-3-3 protein zeta/delta, 14-3-3 delta, 14-3-3 protein/cytosolic phospholipase A2, 14-3-3 zeta, epididymis luminal protein 4, epididymis secretory protein Li 3, epididymis secretory protein Li 93, phospholipase A2, protein kinase C inhibitor protein-1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide, zeta polypeptide, tyrosine 3/tryptophan 5 -monooxygenase activation protein, P63104, Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta, Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Delta Polypeptide, Zeta Polypeptide, 14-3-3 Delta, 14-3-3 Zeta, Tyrosine 3/Tryptophan 5 -Monooxygenase Activation Protein, 14-3-3 Protein/Cytosolic Phospholipase A2, Protein Kinase C Inhibitor Protein-1, Protein Kinase C Inhibitor Protein 1, Epididymis Secretory Protein Li 93, Epididymis Secretory Protein Li 3, Epididymis Luminal Protein 4, 14-3-3 Protein Zeta/Delta, Phospholipase A2, 14-3-3-Zeta, 14-3-3 zeta/YWHAZ
Symbol: YWHAZ
Category: Monoclonal Antibodies
Research Use Only