4-1BB/CD137 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A22167-20, A22167-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Synonyms: ILA; 4-1BB; CD137; CDw137; IMD109; 4-1BB/CD137
GeneID: 3604
Swiss-Prot: Q07011
Reactivity: Human
Tested Applications: ELISA, WB
Calculated Molecular Weight: 28kDa
Observed Molecular Weight: 24-28kDa 40-50kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-186 of human 4-1BB/CD137 (NP_001552.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Cancer, Tumor immunology, Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, CDs, Cytokines, NF-kB Signaling Pathway, Cell Intrinsic Innate Immunity Signaling Pathway, Stem Cells, Hematopoietic Progenitors
Recommended Dilutions: WB: 1:2000 - 1:20000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Membrane, Single-pass Type I Membrane Protein
Positive Samples: 293T transfected with 4-1BB/CD137
Keywords: 3604, TNFRSF9, 4-1BB, CD137, CDw137, ILA, TNF receptor superfamily member 9, tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CD137 antigen, T cell antigen ILA, T-cell antigen 4-1BB homolog, homolog of mouse 4-1BB, induced by lymphocyte activation (ILA), interleukin-activated receptor, homolog of mouse Ly63, receptor protein 4-1BB, Q07011, TNF Receptor Superfamily Member 9, T-Cell Antigen 4-1BB Homolog, 4-1BB Ligand Receptor, CD137 Antigen, Interleukin-Activated Receptor, Homolog Of Mouse Ly63, Tumor Necrosis Factor Receptor Superfamily, Member 9, Tumor Necrosis Factor Receptor Superfamily Member 9, Induced By Lymphocyte Activation (ILA), Homolog Of Mouse 4-1BB, Receptor Protein 4-1BB, T Cell Antigen ILA, T-Cell Antigen ILA, 41BB, 4 1BB, 免疫, 炎症, 天然免疫, 感染, 病毒, 自身免疫, 免疫检查点, Immuno-checkpoints, PD-L1, PD-1, TIM3, CTLA-4, B7-H3, B7-H4, LAG3, VISTA, IDO, Arginase 1, SIGLEC, HVEM, CD39, CD73, CD47, 4-1BB/CD137
Symbol: TNFRSF9
Category: Monoclonal Antibodies
Research Use Only