A-RAF Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A8687-20, A8687-100
Citations, Manuals and SDS Available upon request.
Background: Enables protein serine/threonine kinase activity. Involved in negative regulation of apoptotic process; regulation of TOR signaling; and regulation of cellular protein metabolic process. Predicted to be active in cytosol and mitochondrion. Biomarker of high grade glioma.
Synonyms: PKS2; A-RAF; ARAF1; RAFA1
GeneID: 369
Swiss-Prot: P10398
Reactivity: Human
Calculated Molecular Weight: 68kDa
Observed Molecular Weight: 68kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 166-290 of human A-RAF (P10398).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Protein phosphorylation, Cancer, Signal Transduction, G protein signaling, Small G proteins, Kinase, Serine threonine kinases, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, ESC Pluripotency and Differentiation, Immunology Inflammation, T Cell Receptor Signaling Pathway, Jak-Stat-IL-6 Receptor Signaling Pathway, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, MCF7
Cellular Location: Cytosol, Mitochondrion
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.