ABCD1 / ALD Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A23569-20, A23569-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.
Synonyms: ALD; AMN; ALDP; ABC42; ABCD1 / ALD
GeneID: 215
Swiss-Prot: P33897
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 83kDa
Observed Molecular Weight: 83kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 650-745 of human ABCD1 / ALD (NP_000024.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Multi-pass Membrane Protein, Peroxisome Membrane
Positive Samples: Hep G2, HeLa, NIH/3T3
Keywords: sc-21378, sc-31875, sc-31876, sc-20971, ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN, ATP binding cassette subfamily D member 1, ATP-binding cassette sub-family D member 1, ATP-binding cassette, sub-family D (ALD), member 1, adrenoleukodystrophy protein, P33897, 215, sc21378, sc 21378, sc31875, sc 31875, sc31876, sc 31876, sc20971, sc 20971, ABCD1 / ALD
Symbol: ABCD1
Category: Monoclonal Antibodies
Research Use Only