ABCE1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9135-20, A9135-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
Synonyms: RLI; OABP; RLI1; ABC38; RNS4I; RNASEL1; RNASELI; ABCE1
GeneID: 6059
Swiss-Prot: P61221
Reactivity: Human, Mouse
Calculated Molecular Weight: 67kDa
Observed Molecular Weight: 67kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500-599 of human ABCE1 ( NP_002931.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Immunology Inflammation
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, HT-29, K-562, Mouse liver, Mouse spleen, Mouse pancreas
Cellular Location: Cytoplasm, Mitochondrion
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.