
ACADM Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4567-20, A4567-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: MCAD; ACAD1; MCADH; ACADM
GeneID: 34
Swiss-Prot: P11310
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 47kDa
Observed Molecular Weight: 45kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ACADM (P11310).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Lipid Metabolism, Cardiovascular, Lipids, Fatty Acids
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, 293T, Hep G2, Mouse liver, Mouse heart, Rat liver, Rat heart
Cellular Location: Mitochondrion Matrix,
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.