ACE (N-terminus) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB0114-50, MB0114-100
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P12821
Host: Mouse
Reactivity: Human, Mouse
Applications: WB
All Applications: WB:1:1000
Background: Angiotensin-converting enzyme (ACE) is a carboxy-terminal dipeptidyl exo-peptidase that converts Angiotensin I to the potent vasopressive hormone, Angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically, late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in fluid/electrolyte homeostasis.
Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ACE (N-terminus) mAb detects endogenous levels of Angiotensin-converting enzyme protein.
Bioworld Molecular Weight: Predicted band size:150KDa
Observed band size:195KDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western BlotDetection of ACE (N-terminus) antibody in Mouse kidney cell lysates using ACE (N-terminus) antibody (1:1000 diluted).
Alternative Name: Angiotensin-converting enzyme; Short name=ACE; Dipeptidyl carboxypeptidase I; CD143; ACE1; DCP; DCP1; Angiotensin Converting Enzyme 1
Immunogen: Synthetic peptide, corresponding to the N-terminus of Human ACE.
Conjugate: Unconjugated
Modification: Unmodified