CD30 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9789-20, A9789-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Synonyms: CD30; Ki-1; D1S166E
GeneID: 943
Swiss-Prot: P28908
Reactivity: Human, Rat
Calculated Molecular Weight: 64kDa
Observed Molecular Weight: 120kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 496-595 of human CD30 (P28908).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Tumor immunology, Tumor biomarkers, Signal Transduction, PI3K-Akt Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, CDs, Cytokines, NF-kB Signaling Pathway, Cell Intrinsic Innate Immunity Signaling Pathway, Stem Cells
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: A-549
Cellular Location: Cytoplasm, Extra Cellular Exosome, Plasma Membrane
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.