CD3D Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9770-20, A9770-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Synonyms: T3D; IMD19; CD3DELTA; CD3-DELTA; CD3D
GeneID: 915
Swiss-Prot: P04234
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 19kDa
Observed Molecular Weight: 23kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 72-171 of human CD3D (P04234).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC, FC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IF/ICC: 1:50 - 1:200 | FC: 1:50 - 1:200
Research Areas: Cancer, Tumor immunology, Tumor-associated antigens, Immunology inflammation, CDs, T cell receptor signaling pathway, Stem cells, Hematopoietic progenitors
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Jurkat
Cellular Location: Membrane, Single-pass Type I Membrane Protein
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.