CDC25B Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9758-20, A9758-100
Citations, Manuals and SDS Available upon request.
Background: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Synonyms: CDC25B; cell division cycle 25B
GeneID: 994
Swiss-Prot: P30305
Reactivity: Human
Calculated Molecular Weight: 65kDa
Observed Molecular Weight: 60kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CDC25B (P30305).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Cancer, Kinase, Cell Biology Developmental Biology, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, Hep G2, Raji
Cellular Location: Cytoplasm, Centrosome, Cytoskeleton, Microtubule Organizing Center, Spindle Pole,
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.