ANKH Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9881-20, A9881-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia.
Synonyms: ANK; CMDJ; HANK; MANK; CCAL2; CPPDD; SLC62A1; ANKH
GeneID: 56172
Swiss-Prot: Q9HCJ1
Reactivity: Human
Calculated Molecular Weight: 54kDa
Observed Molecular Weight: 54kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-320 of human ANKH (NP_473368.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Extracellular Matrix, Bone
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SH-SY5Y, OVCAR3
Cellular Location: Membrane, Multi-pass Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.