ATP1B2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9928-20, A9928-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms: AMOG; ATP1B2
GeneID: 482
Swiss-Prot: P14415
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 33kDa
Observed Molecular Weight: 42kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 68-290 of human ATP1B2 (NP_001669.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200
Research Areas: Signal Transduction, Endocrine Metabolism
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HepG2, NCI-H460, SH-SY5Y
Cellular Location: Cell Membrane, Single-pass Type II Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.