BAF60a Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9950-20, A9950-100
Citations, Manuals and SDS Available upon request.
Background: Predicted to enable several functions, including chromatin binding activity; molecular adaptor activity; and transcription coregulator activity. Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation; nucleosome disassembly; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization and nervous system development. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and retina layer. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome. Orthologous to human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1).
Synonyms: Baf60a; D15Kz1; BAF60a
GeneID: 83797
Swiss-Prot: Q96GM5
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 58kDa
Observed Molecular Weight: 58kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of mouse BAF60a (NP_114030.2).
Immunogen Species: Mouse
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics & Nuclear Signaling, Nuclear Receptor Signaling, Nuclear hormone receptors, Chromatin Remodeling, Signal Transduction
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SH-SY5Y, 293T, HepG2, BT-474, K-562, Mouse brain, Rat testis
Cellular Location: Nucleus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.