CAMKK2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9899-20, A9899-100
Citations, Manuals and SDS Available upon request.
Background: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.
Synonyms: CAMKK; CAMKKB; CAMKK2
GeneID: 10645
Swiss-Prot: Q96RR4
Reactivity: Human, Mouse
Calculated Molecular Weight: 65kDa
Observed Molecular Weight: 68kDa/70kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CAMKK2 (NP_006540.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Kinase, Serine threonine kinases, Cell Biology Developmental Biology, Autophagy, Endocrine Metabolism, AMPK Signaling Pathway, Neuroscience, Calcium Signaling
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, SH-SY5Y, LNCaP
Cellular Location: Cell Projection, Cytoplasm, Nucleus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.