CLDN10 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9853-20, A9853-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.
Synonyms: OSPL; HELIX; OSP-L; CPETRL3; CLDN10
GeneID: 9071
Swiss-Prot: P78369
Reactivity: Rat
Calculated Molecular Weight: 24kDa
Observed Molecular Weight: 26kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CLDN10 (NP_008915.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Rat lung
Cellular Location: Cell Junction, Cell Membrane, Multi-pass Membrane Protein, tight Junction
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.