
Histone H2A.1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9895-20, A9895-100
Citations, Manuals and SDS Available upon request.
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Synonyms: H2A/c; H2AFC; H2AC11; H2AC15; H2AC16; H2AC17; HIST1H2AI; Histone H2A.1
GeneID: 3012/8329
Swiss-Prot: P04908/P0C0S8
Reactivity: Human, Mouse, Rat, Other (Wide Range Predicted)
Calculated Molecular Weight: 14kDa
Observed Molecular Weight: 14kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human Histone H2A.1 (NP_064707.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: MCF7, SW480, A-549, HeLa, K-562, Mouse heart, Mouse intestine
Cellular Location: Chromosome, Nucleus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.