ITGAE Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9934-20, A9934-100
Citations, Manuals and SDS Available upon request.
Background: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
Synonyms: CD103; HUMINAE; ITGAE
GeneID: 3682
Swiss-Prot: P38570
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 130kDa
Observed Molecular Weight: 25kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-200 of human ITGAE (NP_002199.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500
Research Areas: Signal Transduction, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Immunology Inflammation, CDs, Stem Cells, Hematopoietic Progenitors
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse testis, Mouse spleen, Mouse thymus, Rat testis, Rat thymus
Cellular Location: Membrane, Single-pass Type I Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.