MRPS16 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9874-20, A9874-100
Citations, Manuals and SDS Available upon request.
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described.
Synonyms: S16mt; COXPD2; RPMS16; CGI-132; MRP-S16; MRPS16
GeneID: 51021
Swiss-Prot: Q9Y3D3
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 15kDa
Observed Molecular Weight: 15kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human MRPS16 (NP_057149.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Endocrine Metabolism, Mitochondrial metabolism
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, Jurkat, SW620, HT-1080, MCF7, Mouse heart, Mouse kidney, Mouse liver, Rat brain
Cellular Location: Mitochondrion
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.