RGS10 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9948-20, A9948-100
Citations, Manuals and SDS Available upon request.
Background: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms: RGS10
GeneID: 6001
Swiss-Prot: O43665
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 21kDa
Observed Molecular Weight: 20kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human RGS10 (NP_001005339.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, HepG2, HT-1080, Jurkat, Rat brain
Cellular Location: Cytoplasm, Cytosol, Nucleus, Plasma Membrane, Synapse,
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.