SERPINB6 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9944-20, A9944-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
Synonyms: CAP; PI6; PTI; PI-6; SPI3; DFNB91; MSTP057; SERPINB6
GeneID: 5269
Swiss-Prot: P35237
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 43kDa
Observed Molecular Weight: 42kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SERPINB6 (NP_004559.4).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Cell Biology Developmental Biology, Ubiquitin
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, Mouse liver, Rat liver
Cellular Location: Cytoplasm
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.