TFR2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9845-20, A9845-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms: HFE3; TFRC2; TFR2
GeneID: 7036
Swiss-Prot: Q9UP52
Reactivity: Human, Mouse
Calculated Molecular Weight: 89kDa
Observed Molecular Weight: 100kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-330 of human TFR2 (NP_003218.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Cardiovascular, Blood
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: K-562, Mouse liver
Cellular Location: Cell Membrane, Cytoplasm, Single-pass Type II Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.