TRIP12 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9958-20, A9958-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.
Synonyms: ULF; MRD49; TRIPC; TRIP-12; TRIP12
GeneID: 9320
Swiss-Prot: Q14669
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 220kDa
Observed Molecular Weight: 260kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human TRIP12 (NP_001271143.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:100
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint, Ubiquitin, Ubiquitin-Proteasome Signaling Pathway
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, Jurkat
Cellular Location: Nucleus, Nucleoplasm
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.