UBTF Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9847-20, A9847-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.
Synonyms: UBF; UBF1; UBF2; UBF-1; CONDBA; NOR-90; UBTF
GeneID: 7343
Swiss-Prot: P17480
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 89kDa
Observed Molecular Weight: 84kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-440 of human UBTF (NP_055048.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Signal Transduction, MAPK-Erk Signaling Pathway
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, MCF7, HL-60, SW620, Mouse kidney, Rat kidney
Cellular Location: Nucleus, Nucleolus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.