Nucleophosmin Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB66878-50, MB66878-100
Product: Mouse IgG1. Supplied in crude ascites with 0.01% sodium azide.
Swiss-Prot: P06748
Host: Mouse
Reactivity: Human, Rat
Applications: WB
All Applications: WB (1/500 - 1/1000)
Background: Nucleophosmin is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase 伪 activity, centrosome duplication and molecular chaperoning activities . The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase .
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Recognizes endogenous levels of Nucleophosmin protein.
Bioworld Molecular Weight: ~ 38 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Nucleophosmin expression in rat heart (A) whole cell lysates., ???, ???, ???
NPM; Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
Immunogen: Recombinant fusion protein of human Nucleophosmin. The exact sequence is proprietary.
Conjugate: Unconjugated
Modification: Unmodified