Recombinant Human Lipopolysaccharide-binding protein/LBP Protein
Size: 10UG
Catalogue Numbers: RP00418-10
Citations, Manuals and SDS Available upon request.
Description: Recombinant Human Lipopolysaccharide-binding protein/LBP Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ala26-Val481) of human LBP/Lipopolysaccharide-binding protein (Accession #P18428) fused with a 6×His tag at the C-terminus.
Background: This protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
Synonyms: BPIFD2, LBP
Swiss-Prot: P18428
GeneID: 3929
Species: Human
Purity: > 95% by SDS-PAGE.
Research Areas: Other Recombinant Protein
Expression System: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.2. Contact us for customized product form or formulation.
Endotoxin: < 1 EU/μg of the protein by LAL method.
Symbol: Lipopolysaccharide-binding
Storage: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Keywords: Recombinant Human LBP/Lipopolysaccharide-binding protein Protein, LBP, BPIFD2
Research Use Only