Recombinant Human TIE2/TEK/CD202b Protein
Size: 10UG
Catalogue Numbers: RP00048-10
Citations, Manuals and SDS Available upon request.
Description: Recombinant Human TIE2/TEK/CD202b Protein is produced by insect cell-baculovirus expression system. The target protein is expressed with sequence (Lys808-Ala1124) of human hTIE2 (Accession #NP_000450.2).
Background: Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angiogenesis, depending on the context. Inhibits angiogenesis and promotes vascular stability in quiescent vessels, where endothelial cells have tight contacts.
Synonyms: TEK, CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1, Tie2
Swiss-Prot: Q02763
GeneID: 7010
Species: Human
Purity: > 97% by SDS-PAGE.
Research Areas: Bio-Markers & CD Antigens, Growth Factor
Expression System: Baculovirus-Infected Sf9 Cells
Tag: No tag
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Endotoxin: < 1.0 EU/μg of the protein by LAL method.
Symbol: TIE2/TEK/CD202b
Storage: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Keywords: Recombinant Human hTIE2 Protein, TEK, CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1, CD202B, TIE-2, TIE2, VMCM, VMCM1
Research Use Only