Recombinant Human TNFRSF10C/TRAIL R3 Protein
Size: 10UG
Catalogue Numbers: RP00805-10
Citations, Manuals and SDS Available upon request.
Description: Recombinant Human TNFRSF10C/TRAIL R3 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Ala26-Ala221) of human TNFRSF10C/TRAIL R3 (Accession #O14798) fused with a 6×His tag at the C-terminus.
Background: Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn't transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
Synonyms: TNFRSF10C, CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Swiss-Prot: O14798
GeneID: 8794
Species: Human
Purity: > 95% by SDS-PAGE.
Research Areas: Cytokines & Cytokine Receptors
Expression System: HEK293 cells
Tag: C-6×His
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Contact us for customized product form or formulation.
Endotoxin: < 1 EU/μg of the protein by LAL method.
Symbol: TNFRSF10C/TRAIL R3
Storage: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Keywords: Recombinant Human TNFRSF10C/TRAIL R3 Protein, TRAIL R3, Tumor Necrosis Factor Receptor Superfamily Member 10C, Antagonist Decoy Receptor for TRAIL/Apo-2L, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Lymphocyte Inhibitor of TRAIL, TNF-R
Research Use Only