14-3-3 gamma Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9162-20, A9162-100
Citations, Manuals and SDS Available upon request.
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Synonyms: DEE56; EIEE56; PPP1R170; 14-3-3GAMMA; 14-3-3 gamma
GeneID: 7532
Swiss-Prot: P61981
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 28kDa
Observed Molecular Weight: 28kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human 14-3-3 gamma (P61981).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer, Signal Transduction, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, MAPK-JNK Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint, Neuroscience, Cell Type Marker, Stem Cells, Neuron marker, Synapse marker
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, NIH/3T3, Jurkat, Mouse liver, Mouse heart, Rat lung
Cellular Location: Cytoplasm
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.