GAB2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13066-20, A13066-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
Synonyms: GAB2
GeneID: 9846
Swiss Prot: Q9UQC2
Tested Applications: ELISA, WB
Reactivity: Human, Mouse
Calculated Molecular Weight: 74kDa
Observed Molecular Weight: 74kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 377-676 of human GAB2 (NP_536739.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Cancer, Signal Transduction, PI3K-Akt Signaling Pathway, ErbB-HER Signaling Pathway, Immunology Inflammation, B Cell Receptor Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, Mouse kidney
Cellular Location: Cell Membrane, Cytoplasm,
Keywords: 9846, sc-9313, sc-9311, sc-25498, GAB2, GRB2 associated binding protein 2, GRB2-associated-binding protein 2, Grb2-associated binder 2, growth factor receptor bound protein 2-associated protein 2, pp100, Q9UQC2, GRB2 Associated Binding Protein 2, Growth Factor Receptor Bound Protein 2-Associated Protein 2, Grb2-Associated Binder 2, Pp100, GRB2-Associated-Binding Protein 2, GRB2-Associated Binder 2, KIAA0571, A0619, sc9313, sc 9313, sc9311, sc 9311, sc25498, sc 25498, GRB2 associated binder 2
Symbol: GAB2
Category: Polyclonal Antibodies
Research Use Only