[KO Validated] Emerin/EMD Rabbit pAb - A18030

[KO Validated] Emerin/EMD Rabbit pAb

Sizes: 20µl, 100µl

Catalogue Numbers: A18030-20, A18030-100

Citations, Manuals and SDS Available upon request.

Background: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.

Synonyms: STA; EDMD; LEMD5; MD

GeneID: 2010

Swiss-Prot: P50402

Reactivity: Human, Mouse

Tested Applications: ELISA, WB, IF/ICC

Calculated Molecular Weight: 29kDa

Observed Molecular Weight: 30kDa

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Emerin/Emerin/EMD (NP_000108.1).

Immunogen Species: Human

Host: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.

Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Intermediate Filaments

Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200

Modifications: Unmodified

Conjugate: Unconjugated

Cellular Location: Nucleoplasmic side, Nucleus Inner Membrane, Nucleus Outer Membrane, Single-pass Membrane Protein

Positive Samples: 293T

Keywords: 2010, sc-8085, sc-8084, sc-8086, sc-15378, EDMD, EMD, Emerin, LEMD5, STA, emerin, LEM domain containing 5, P50402, LEM Domain Containing 5, Emery-Dreifuss Muscular Dystrophy, marker, Nuclear envelope, Nuclear envelope marker, MD

Symbol: EMD

Category: Polyclonal Antibodies

Research Use Only