Laminnin α3 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90786-50, BS90786-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q16787(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, ICC/IF
All Applications: WB:1:1,000-1:2,000
ICC:1:100-1:500
Background: Laminins are heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. Through interactions with integrins, dystroglycan and other receptors, laminins contribute to cell differentiation, cell shape and migration, and maintenance of tissue phenotypes and survival. Laminin alpha 3/Laminin-5, also known as epiligrin, includes alpha 3, beta 3, and gamma 2 subunits. It is abundant in transitional epithelium, stratified squamous epithelia, lung mucosa and other epithelial glands and contributes to initiation and maintenance of epithelial cell anchorage to the underlying connective tissue. Within aa 21?1713 of the alpha 3 subunit, human and mouse share 77% amino acid sequence identity.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Laminnin α3 polyclonal antibody detects endogenous levels of Laminnin α3 protein.
Bioworld Molecular Weight: 367 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Laminnin 5 alpha 3 on A431 cells lysates using anti-Laminnin 5 alpha 3 antibody at 1/1,000 dilution., ICC staining Laminnin 5 alpha 3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: E170, LAMA3, E170, Epiligrin 170 kDa subunit, Epiligrin subunit alpha, Kalinin subunit alpha, LAMA3, LAMA3A, Laminin 5 alpha3, Laminin A3, laminin alpha 3, laminin alpha3, Laminin subunit alpha-3, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, laminin5 alpha 3, Laminin5 alpha3, LAMNA, LOCS, Nicein subunit alpha,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified