Sarcoglycanγ Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91205-50, BS91205-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q13326(Human)
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB, IP, IHC
All Applications: WB:1:500-1:2,000
IP:1:50-1:100
IHC:1:50-1:200
Background: The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Sarcoglycanγ polyclonal antibody detects endogenous levels of Sarcoglycanγ protein.
Bioworld Molecular Weight: 32 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of gamma Sarcoglycan on human skeletal muscle cells lysates using anti- gamma Sarcoglycan antibody at 1/500 dilution., Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-gamma Sarcoglycan antibody. Counter stained with hematoxylin.
Alternative Name: Gamma-SG, 35DAG, SGCG, 35 kDa dystrophin associated glycoprotein, 35 kDa dystrophin-associated glycoprotein, 35DAG, 35kD dystrophin associated glycoprotein, 35kDa dystrophin-associated glycoprotein, A4, DAGA4, DMDA, DMDA1, Gamma SG, Gamma-sarcoglycan, Gamma-SG, LGMD2C, MAM, MGC130048, Sarcoglycan gamma, SCARMD2, SCG3, SGCG, SGCG, TYPE,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified