TIN2/TINF2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9750-20, A9750-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.
Synonyms: TIN2; DKCA3; TIN2/TINF2
GeneID: 26277
Swiss-Prot: Q9BSI4
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 50kDa
Observed Molecular Weight: 45kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-309 of human TIN2/TINF2 (Q9BSI4).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Hep G2, A549, Mouse testis, Mouse thymus, Rat lung, Rat testis
Cellular Location: Chromosome, Nucleus, Nucleus Matrix, Telomere
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.